Share 26 Views no discussions A run of poor sleep can have a potentially profound effect on the internal workings of the human body, say UK researchers.The activity of hundreds of genes was altered when people’s sleep was cut to less than six hours a day for a week.Writing in the journal PNAS, the researchers said the results helped explain how poor sleep damaged health.Heart disease, diabetes, obesity and poor brain function have all been linked to substandard sleep.What missing hours in bed actually does to alter health, however, is unknown.So researchers at the University of Surrey analysed the blood of 26 people after they had had plenty of sleep, up to 10 hours each night for a week, and compared the results with samples after a week of fewer than six hours a night. More than 700 genes were altered by the shift. Each contains the instructions for building a protein, so those that became more active produced more proteins – changing the chemistry of the body.Meanwhile the natural body clock was disturbed – some genes naturally wax and wane in activity through the day, but this effect was dulled by sleep deprivation.Prof Colin Smith, from the University of Surrey, told the BBC: “There was quite a dramatic change in activity in many different kinds of genes.” Areas such as the immune system and how the body responds to damage and stress were affected.Prof Smith added: “Clearly sleep is critical to rebuilding the body and maintaining a functional state, all kinds of damage appear to occur – hinting at what may lead to ill health. “If we can’t actually replenish and replace new cells, then that’s going to lead to degenerative diseases.”He said many people may be even more sleep deprived in their daily lives than those in the study – suggesting these changes may be common.Dr Akhilesh Reddy, a specialist in the body clock at the University of Cambridge, said the study was “interesting”. He said the key findings were the effects on inflammation and the immune system as it was possible to see a link between those effects and health problems such as diabetes.The findings also tie into research attempting to do away with sleep, such as by finding a drug that could eliminate the effects of sleep deprivation. Dr Reddy said: “We don’t know what the switch is that causes all these changes, but theoretically if you could switch it on or off, you might be able to get away without sleep.“But my feeling is that sleep is fundamentally important to regenerating all cells.”By James GallagherBBC News Share Share Tweet HealthLifestyle Bad sleep ‘dramatically’ alters body by: – February 26, 2013 Sharing is caring!
Through Nacosa’s efforts, HIV incidence rates and mother-to-child transmissions have dropped in South Africa, and the country’s anti-retroviral treatment has become the biggest in the world.When Maureen Van Wyk joined Networking HIV, Aids Community of South Africa (Nacosa) in 2005, it was a small operation with a handful of staff operating on a limited budget within the Western Cape. Under her leadership, Nacosa has grown into a major player in the HIV/AIDS and TB field with a national network of 1 500 organisations, over 70 staff and channels resources to deliver services on the ground in all nine provinces.“I’ve worked in government and I’ve worked at a university and I’ve chosen to work in civil society because of the dynamic nature of it, the engagement and interaction with issues,” says Van Wyk when asked why she has chosen to work within civil society for so long. “Unlike in government, there is not much bureaucracy and one can really make a difference and actually see the difference that one makes.”Van Wyk, who has a PhD in social development from the University of Pretoria, has noticed a sea of change in the sector over the last ten years: “It has become more professional and more accountable because donors expect to see value for their money. In the past, many organisations were funded without clear deliverables but now the scenario has changed. Many NGOs have gone under but others have grown.”Maureen van Wyk has been at the helm of Nacosa for the last ten years. Her leadership has made Nacosa a vital cog in South Africa’s battle against HIV/Aids. (Image: Nacosa)HIV RESPONSE“The HIV response has grown tremendously,” says Van Wyk. “Ten years ago was just the beginning of [anti-retroviral] treatment in South Africa and today we have the largest treatment programme in the world. The knowledge and information we had back then was very limited whereas today we have a fantastic multi-sectoral HIV response in the country in terms of prevention, treatment, care and human rights.”The fruits of this coordinated response are being realised with declining incidence rates, increased life expectancy and a dramatic reduction in mother-to-child HIV transmission.The burgeoning HIV response is mirrored by Nacosa’s own growth. “I think my greatest achievement is building Nacosa from a small Western Cape-focused organisation to an organisation that significantly participates and impacts on the HIV response in the country,” Van Wyk reflects. “We now work in all provinces and thousands of people at grassroots level benefit from the funding that we manage.”As Principal Recipient for the Global Fund alone, Nacosa has channelled over $60 million (R788-million) to community organisations across the country, achieving an A1 rating – the highest – for the duration of Phase I of the grant.CHALLENGESBut growth and success hasn’t come without its challenges, the biggest of which has been accessing sustainable and consistent funding from local donors. “If you look at the funding scenario right now, you will find that the HIV response is largely funded by international donors. We would have liked more funding to come from local donors and government.”Funding and resource issues are by far the biggest challenge facing Nacosa member organisations at the moment. The majority of respondents in a recent member survey reported lack of funding (63%), staffing or human resource shortages (44%), unreliable or inconsistent funding (41%) and access to information about funding and other opportunities (30%) as major challenges. Lack of technical skills was listed by 20% of respondents and staff retention, funding for salaries, lack of equipment and office space, and “lack of local political will” were also reported by some members.“I would like to see a better, more committed government response in terms of funding for civil society in South Africa,” says Van Wyk. “We work at grassroots level, where government cannot reach, and we need more sustainable funding streams from local government as well as provincial government.”The current trend towards the pooling of corporate social investment funding for health and education is further eroding access to funding by small, grassroots organisations. Despite her wish for more meaningful engagement with local donors, Van Wyk cautions: “It is vital that international funding also stays consistent to maintain our current HIV response.”WOMEN IN LEADERSHIP“What is challenging women in South Africa is the old, out-dated, patriarchal way of thinking about gender roles and what is expected and what is not expected of a woman,” notes Van Wyk. “Honestly, this also affects the men because gender stereotyping prevents people, both males and females, from being the person they could be and want to be.“Women in management positions, particularly in civil society, face many challenges: fundraising, managing a diverse staff as well as running all their programs. Unlike in other institutions where you have a lot of support functions, in the NGO sector, the leader has to be multi-skilled. Luckily for me, Nacosa has more support systems in place and we’ve got fantastic staff.”An informed, skilled and committed board has also been a great support to Van Wyk over the years.ADVICEAs for her advice to other women – or men – in civil society leadership roles: “It is important to keep your strategic focus, even through difficult times, to see the bigger picture.“We have many strong examples of women leading NGOs in South Africa. My advice is to remain focused, passionate and always keep your integrity. It is important to find a balance between the work that needs to be done and making sure that your staff works in an environment where they feel respected.”Source: SANGONeT Pulse
Share Facebook Twitter Google + LinkedIn Pinterest Today USDA again provided a surprise as they increased the corn yield more than expected. The soybean yield was unchanged. Brazil’s soybean production was higher, a bit bearish. The soybean carryout was reduced, that was expected.USDA estimated the U.S. corn yield at 175.4 bushels per acre, up from last month’s 171.8. Traders were looking for the corn yield and production to increase slightly compared to the October report. USDA estimated the U.S. soybean yield at 49.5 bushels per acre, that was unchanged. USDA had the corn ending stocks at 2.487 billion bushels. Last month they were 2.34 billion bushels. Soybean ending stocks were estimated at 425 million bushels. Last month they were 430 million bushels.Minutes after the report corn was down 3 cents, soybeans down 4 cents, and wheat up 2 cents. Just before the noon report, corn was unchanged, soybeans were up 5 cents, with wheat up 3 cents.Corn prices have been very boring for at least the last month. Daily price ranges have often been 2 to 3 cents from the day’s high to the day’s low. Earlier this week corn spent much of the day trading with just a one cent daily range. It has been a common thread for the past month that the report today would show corn yields increasing while soybean yields were expected to decline. December CBOT corn since Sept. 1 has seen a high of $3.62 and a low of $3.425. The past six weeks it has seen a high of $3.5525 and a low of $3.425. That low was made with the Oct. 12 report when the corn yield increased almost two bushels per acre. Corn has had difficulty trading above $3.50 and below $3.45.The average trade estimate for the corn yield was 172.4 bushels per acre. Meanwhile, the average soybean yield by traders was pegged at 49.3 bpa compared to 49.5 bpa from last month. Corn ending stocks were projected to increase slightly while seeing the soybean ending stocks decline by a very small number. Corn and soybean volumes have been very light in overnight trading many days this past month.Ohio producers are looking for a break in the weather to finish corn and soybean harvest. Last weekend’s rainfall totals for much of the state exceeded 3 inches while reaching almost 5 inches in south central Ohio. That rainfall has kept many producers out of the fields early this week. A small number were back harvesting on Wednesday. The huge amount of corn and soybean replant acres this spring had kept producers out of those fields with maturity taking place slower than desired. Unfortunately, with the change in the weather, daily highs are struggling to be in the 50s. Those temperatures combined with cloudy days result in very little field drying. Daily lows the next two mornings in the low 20s are in the forecast. Western Ohio had heavy winds on Sunday that did extensive damage. Those winds did not follow all the way across the state.Weather in South America has been the wild card in recent weeks. Soybeans have not collapsed for days in a row with recent rains in northern Brazil. Earlier in October it was too wet in Argentina and southern Brazil while too dry in northern Brazil. Soybean planting in Brazil has been at a slower pace than in past year as farmers waited until mid-September and later to begin planting soybeans. Waiting for moisture was the reason for delays. Late last week Brazil’s farmers were heavy sellers of soybeans as their currency declined.The next monthly supply and demand report will be Dec. 12. That report will not detail corn and soybean yields and production as those numbers will be unchanged from November. The Jan. 12, 2018 USDA report will detail final yields and production for corn and soybeans. The January report will also publish U.S. quarterly grain stocks as of Dec. 1, 2017.Quickly dismissed earlier today was the corn export sales report of 93 million bushels. Today’s sales are the third largest weekly corn sales since October 2007. The record in the past 15 years appears to be the late October 2013 sales report that combined several weeks of sales at 179 million bushels. The government shutdown Oct. 1-16, 2013 prevented USDA from compiling reports for several weeks.Most important today will be the corn close. Will it make new contract lows?
Manly Warringah is one of the top affiliates in NSW, not only for their on the field performances but also their off field performances. Graham’s has been instrumental in this success. His vision of ensuring that the club has policies and procedures for every aspect of their operations has laid out a clear and concise platform to ensure not just success but also sustainability in one of the most competitive environments and landscapes in NSW.This platform paved by Graham importantly is having a great impact at grass roots level and the growth of the organisation. His and his clubs work is not just having an impact with the Manly Warringah TA, but also with other affiliates across the state. Many of whom are looking to Manly to replicate their success by following the programs and principles laid down by Graham and his team. Importantly Graham is willing to share his experiences with other affiliates and members.
Liverpool boss Klopp: 6 points are nothing. We’re creating our own historyby Paul Vegas10 months agoSend to a friendShare the loveLiverpool boss Jurgen Klopp isn’t getting carried away after victory over Newcastle United.The Reds have been installed as the new title favourites after they comfortably beat Newcastle 4-0 and Manchester City lost for successive matches, going down 2-1 at Leicester City.Now six points clear at the top of the table, Klopp said: “That means nothing. We play Arsenal and City. I had no idea how any other teams were playing, I didn’t even know where they were playing.”Afterwards I got the results and I can say it didn’t do a lot for me. It is just information. It’s good that we have six points than other teams, or seven, but that is pretty much all.”Klopp added: “We want to create our own history. It is the first Liverpool team in the Premier League unbeaten (at the halfway stage of the season).”All good numbers but there are 19 games to go. So we play Arsenal, we play City, we play Tottenham. We play all of them again. There is a long way to go, we all know that.”We have to win our games we have to be focused, we have to be really in the mood and have tunnel vision and see where it leads us to.” About the authorPaul VegasShare the loveHave your say
About the authorFreddie TaylorShare the loveHave your say Ex-Man City keeper Hart hails David Silva: He was tiny, slow and one-footed!by Freddie Taylor24 days agoSend to a friendShare the loveFormer Manchester City goalkeeper Joe Hart still marvels at the transformation of David Silva since he joined the club.Silva arrived in England in 2010 with a big reputation from his success with Valencia.However, Hart recalls the little midfielder appearing tiny, slow and extremely one footed in early training sessions.Silva has gone on to become one of City’s greatest ever players.The former City goalkeeper told the Kickback podcast: “The wizard came over, I had no idea who he was.”£25 million, tiny, slow, only left footed and didn’t even know his position.”He seemed like a lovely guy, didn’t really speak much English.”He didn’t take over straight away but his consistency and quality were through the roof.”Just an all-round amazing player – there isn’t one negative to him, other than he’s small.”
About the authorPaul VegasShare the loveHave your say Norwich City boss Farke sorry with Godfrey injuryby Paul Vegas6 days agoSend to a friendShare the loveNorwich City boss Daniel Farke admits Ben Godfrey’s injury is a blow after 0-0 draw wit Aston Villa,Norwich’s injury woes continued as Godfrey was forced off shortly after the break.”We have to wait and see what the outcome is [with Ben Godfrey],” Farke said. “He had hernia surgery 10 days ago and he only had one [training] session with the team.”He was top class in the first 50 minutes and it was important to have him on the pitch – he was a great leader. After 50 minutes he felt pain, I think his body was getting tired after only one session, I hope it’s not a big setback, but I hope to have him available for Man United but we have to wait.”
joel klatt cardale jones fox sportsSaturday, Ohio State, for the first time this season, will be starting sophomore J.T. Barrett over junior Cardale Jones at quarterback. Most college football analysts are applauding the move, given Jones’ struggles this year. Fox Sports’ Joel Klatt agrees, and even went one step further when he joined Dan Patrick Friday morning.Klatt, using a Thanksgiving analogy, implied that Jones was given too much credit for last year’s national title. He believes that Barrett did most of the work in leading Ohio State to the promised land.Klatt’s right, but he is discounting the fact that Jones, who had never started a college football game, beat Wisconsin, Alabama and Oregon in his first three games. Regardless, Barrett is set to lead the offense, and it has Ohio State fans excited.
Here is a list of all the candidates running in 2018.Trevor Bolin (incumbent)Bruce Christensen (incumbent)Larry Evans (incumbent)Chuck FowlerBecky GrimsrudLilia Hansen (incumbent)Gabor HarisJim HarrisJustin JonesGord Klassen (incumbent)Byron Stewart (incumbent)Tony ZabinskyGet out and vote. You can vote October 10, 17 and 20. The polls will be open from 8 a.m. to 8 p.m. on those days at the Royal Canadian Legion in Fort St. John.Click here to see if your eligible to vote. The 2018 Municipal Election will be held in Fort St. John on October 20 with advance voting opportunities on October 10 and 17. Get out and vote and help pick the next Fort St. John City Council.There are 12 candidates running for six seats on Council. Over the next two weeks, we will share more about each candidate on Moose FM and Energeticcity.ca. We gave each candidate two minutes to tell us why you should vote for them. We will post a video daily in alphabetical order by last name.Our next candidate is Gabor Haris.